pentobarbital will lower the level or effect of alfuzosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Mysterious.

pentobarbital will reduce the level or outcome of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

pentobarbital will lessen the level or effect of rolapitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Long-time period coadministration of robust CYP3A4 inducers with rolapitant may appreciably lower rolapitant efficacy.

pentobarbital will lower the extent or effect of estrogens esterified by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

Psychological, tolerance and physical dependence might come about with continued use; sufferers with psychological dependence on barbiturates may well create a Actual physical dependence on barbiturates by growing or reducing the dosage interval with out consulting a medical doctor

pentobarbital improves toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. CYP3A4 inducers might enhance the metabolism of ifosfamide to its Lively alkylating metabolites.

Contraindicated (one)pentobarbital will reduce the level or effect of roflumilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital boosts results of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Warning/Keep an eye on. Coadministration of ifosfamide with CYP2B6 inducers could raise metabolism of ifosfamide to its metabolite. Check for elevated consequences/toxicities if combined with CYP2B6 inducers.

pentobarbital will lower the level or impact of propafenone more info by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.

pentobarbital will decrease the extent or influence of bosentan by impacting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Mysterious.

pentobarbital will minimize the extent or outcome of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Mysterious.

pentobarbital will minimize the level or result of etoposide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

pentobarbital will decrease the extent or impact of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Strong CYP3A4 inducers may well reduce midostaurin concentrations causing lowered efficacy.

pentobarbital will lower the extent or influence of apremilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration with strong CYP inducers results in an important minimize of systemic exposure of apremilast, which may result in loss of efficacy